It lies immediately under the connective tissue capsule, forming 15% of the cortex.The activated receptor then stimulates the production of ion channels in the renal tubular cells, thereby increasing sodium reabsorption into the blood and increasing potassium excretion into the urine. It acts by binding to and activating a receptor in the cytoplasm of renal tubular cells. The biological action of aldosterone is to increase the retention of sodium and water and to increase the excretion of potassium by the kidneys (and to a lesser extent by the skin and intestines). Angiotensin I is subsequently converted to angiotensin II, which stimulates the release of aldosterone from the adrenal glands. Renin acts on a protein circulating in the plasma called angiotensinogen, cleaving this substance into angiotensin I. Renin is secreted from the kidneys in response to variations in blood pressure and volume and plasma sodium and potassium levels. Production of aldosterone (in adult humans, about 20–200 micrograms per day) in the zona glomerulosa of the adrenal cortex is regulated by the renin-angiotensin system. Pathways in the biosynthesis of steroid hormonesĪldosterone is synthesized in the body from corticosterone, a steroid derived from cholesterol. SpaceNext50 Britannica presents SpaceNext50, From the race to the Moon to space stewardship, we explore a wide range of subjects that feed our curiosity about space!.Learn about the major environmental problems facing our planet and what can be done about them! Saving Earth Britannica Presents Earth’s To-Do List for the 21st Century.Britannica Beyond We’ve created a new place where questions are at the center of learning.

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Adrenal cortex hormones function